RP 72540 is a selective CCK-B receptor antagonist, with IC50 values of 2.4, 1.2, and 3.8 nM for CCK-B receptors in the guinea pig cerebral cortex, rat cerebral cortex, and mouse brain, respectively. RP 72540 effectively inhibits CCK-8-induced neuronal firing and dose-dependently inhibits gastric acid secretion, making it potentially valuable in studies of acid secretion. RP 72540 is an important tool for investigating the physiological functions of CCK B receptors[1].
Molekulargewicht:
518.56
CAS Nummer:
[139088-45-2]
Formel:
C28H30N4O6
Target-Kategorie:
Cholecystokinin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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