TAK-243 (Standard), CAS [[1450833-55-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-100487R
Hersteller Artikelnummer:
HY-100487R
Alternativnummer:
MCE-HY-100487R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
TAK-243 (Standard) is the analytical standard of TAK-243 (HY-100487). This product is intended for research and analytical applications. TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. TAK-243 (MLN7243) induces endoplasmic reticulum (ER) stress, abrogates NF-kappaB pathway activation and promotes apoptosis[1][2].
