VUF10166 is a potent and high-affinity 5-HT3 receptor antagonist, with Ki values of 0.04 nM (5-HT3A) and 22 nM (5-HT3AB). VUF10166 inhibits 5-HT-induced responses at 5-HT3A and 5-HT3AB receptors at nanomolar concentrations. At 5-HT3 receptor, VUF10166 at higher concentrations also acts as a partial agonist, with an EC50 of 5.2 µM[1].
Molekulargewicht:
262.74
Reinheit:
99.83
CAS Nummer:
[155584-74-0]
Formel:
C13H15ClN4
Target-Kategorie:
5-HT Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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