Cl-amidine (hydrochloride) (Standard), CAS [[1373232-26-8]] Preis auf Anfrage
Artikelnummer:
MCE-HY-100574AR
Hersteller Artikelnummer:
HY-100574AR
Alternativnummer:
MCE-HY-100574AR-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Cl-amidine (hydrochloride) (Standard) is the analytical standard of Cl-amidine (hydrochloride) (HY-100574A). This product is intended for research and analytical applications. Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 µM, 6.2 µM and 5.9 µM for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model[1][2][3][4][5].
