AZD5153 is a bivalent, selective, and orally active BET/BRD4 bromodomain inhibitor with an IC50 of value of 5 nM for full-length BRD4 (FL-BRD4). AZD5153 ligates two bromodomains in BRD4 simultaneously. AZD5153 can be used for the study of cancer, such as acute myeloid leukemia, multiple myeloma, and diffuse large B-cell lymphoma[1].
Molekulargewicht:
479.57
Reinheit:
99.20
CAS Nummer:
[1869912-39-9]
Formel:
C25H33N7O3
Target-Kategorie:
Apoptosis,Epigenetic Reader Domain
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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