DPO-1 (Standard), CAS [[43077-30-1]] Preis auf Anfrage
Artikelnummer:
MCE-HY-100712R
Hersteller Artikelnummer:
HY-100712R
Alternativnummer:
MCE-HY-100712R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
DPO-1 (Standard) is the analytical standard of DPO-1 (HY-100712). This product is intended for research and analytical applications. DPO-1 is a potent Kv1.5 and Kv1.3 (EC50 = 3.1 µM) channels inhibitor with potential immunomodulatory and anti-inflammatory effects. DPO-1 reduces Kv1.3 current density, blunts Ca2+ influx in Ca2+-depleted Jurkat cells, and inhibits IL-2 secretion in activated Jurkat cells. DPO-1 inhibits Uric acid sodium (HY-B2130A) (MSU)-induced NLRP3 inflammasome activation by blocking Kv1.5-mediated K+ efflux. DPO-1 can be used for the study of immunologic disorders and atrial fibrillation[1][2][3].
