Quinolinic acid-13C4, 15N is an isotopic labeled Quinolinic acid (HY-100807). Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis.
Molekulargewicht:
172.08
Reinheit:
98.80
Formel:
C3 13C4H5 15NO4
Target-Kategorie:
Apoptosis,Endogenous Metabolite,iGluR,Isotope-Labeled Compounds,NO Synthase,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Isotope-Labeled Compounds
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