Etazolate (hydrochloride) (Standard) is the analytical standard of Etazolate (hydrochloride). This product is intended for research and analytical applications. Etazolate hydrochloride (SQ 20009) is an orally active, selective inhibitor of type 4 phosphodiesterase (PDE4) with an IC50 of 2 µM. Etazolate hydrochloride is a gamma-aminobutyric acid A (GABAA) receptor regulator. Etazolate hydrochloride is an alpha-secretase activator and induced the production of soluble amyloid precursor protein (sAPPalpha). Etazolate hydrochloride, a pyrazolopyridine class derivative, increases cAMP levels. Etazolate hydrochloride has anxiolyticlike, antidepressant-like and anti-inflammatory effects[1][2][3][4][5].
