Suvecaltamide (MK-8998) is a selective T-type calcium channel inhibitor with oral efficacy. Suvecaltamide exhibits no cytotoxicity in myeloma cell lines and does not affect the antitumor efficacy of Bortezomib (BTZ). Suvecaltamide reverses BTZ-induced peripheral neuropathy (CIPN) in mouse and rat models, and helps inhibit myeloma growth[1].
Molekulargewicht:
380.40
Reinheit:
99.96
CAS Nummer:
[953778-58-0]
Formel:
C20H23F3N2O2
Target-Kategorie:
Calcium Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound
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