Silodosin (KAD 3213, KMD 3213) is a potent, selective and orally active alpha1A-adrenergic receptor (alpha1A-AR) blocker. Silodosin exhibits high affinity for alpha1A-AR (Ki=0.036 nM), over 162-fold and 50-fold than for alpha1B-AR and alpha1D-AR with Ki values of 21 nM and 2.0 nM, respectively. Silodosin is an effective and well-tolerated agent, it can be used for the investigation of LUTS/BPH[1][3].
Molekulargewicht:
495.53
Reinheit:
99.82
CAS Nummer:
[160970-54-7]
Formel:
C25H32F3N3O4
Target-Kategorie:
Adrenergic Receptor,Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound
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