YKL-5-124 (TFA), CAS [[2748220-93-9]]

Produktübersicht

• Artikelname: YKL-5-124 (TFA), CAS [[2748220-93-9]]
• Artikelnummer: MCE-HY-101257B
• Hersteller Artikelnummer: HY-101257B
• Alternativnummer: MCE-HY-101257B-25MG, MCE-HY-101257B-5MG, MCE-HY-101257B-10MG, MCE-HY-101257B-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

YKL-5-124 TFA is a potent, selective, irreversible and covalent CDK7 inhibitor with IC50s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively. YKL-5-124 TFA is >100-fold greater selective for CDK7 than CDK9 and CDK2, and inactive against CDK12 and CDK13. YKL-5-124 TFA induces a strong cell-cycle arrest, inhibits E2F-driven gene expression, and exhibits little effect on RNA polymerase II phosphorylation status[1].

Produkteigenschaften

• Molekulargewicht: 629.63
• Reinheit: 99.74
• CAS Nummer: [2748220-93-9]
• Formel: C30H34F3N7O5
• Target-Kategorie: CDK

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound