Trilaciclib (G1T28) is an orally active CDK4/6 inhibitor with IC50 values of 1 nM and 4 nM for CDK4 and CDK6, respectively. . Trilaciclib can effectively inhibit tumor cell proliferation and reduce the hematological toxicity caused by chemotherapy. Trilaciclib attenuates apoptosis and myelosuppression induced by 5FU (HY-90006) chemotherapy[1].
Molekulargewicht:
446.55
Reinheit:
99.42
CAS Nummer:
[1374743-00-6]
Formel:
C24H30N8O
Target-Kategorie:
CDK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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