GZD856 formic is a potent and orally active PDGFRalpha/beta inhibitor, with IC50s of 68.6 and 136.6 nM, respectively. GZD856 formic is also a Bcr-AblT315I inhibitor, with IC50s of 19.9 and 15.4 nM for native Bcr-Abl and the T315I mutant. GZD856 formic has antitumor activity[1][2].
Molekulargewicht:
532.56
CAS Nummer:
[1257628-64-0]
Formel:
C29H27F3N6O
Target-Kategorie:
Apoptosis,Bcr-Abl,PDGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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