BETd-260 (ZBC 260) is a PROTAC connected by ligands for Cereblon and BET, with as low as 30 pM against BRD4 protein in RS4,11 leukemia cell line[1]. BETd-260 potently suppresses cell viability and robustly induces apoptosis in hepatocellular carcinoma (HCC) cells[2].
Molekulargewicht:
798.89
Reinheit:
99.68
CAS Nummer:
[2093388-62-4]
Formel:
C43H46N10O6
Target-Kategorie:
Apoptosis,Epigenetic Reader Domain,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
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