Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death[1].
Molekulargewicht:
409.82
Reinheit:
99.32
CAS Nummer:
[1402055-25-7]
Formel:
C21H16ClN3O4
Target-Kategorie:
CDK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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