Uzansertib (INCB053914) is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib has broad anti-proliferative activity against a variety of hematologic tumor cell lines[1].
Molekulargewicht:
513.51
Reinheit:
99.45
CAS Nummer:
[1620012-39-6]
Formel:
C26H26F3N5O3
Target-Kategorie:
Pim
Anwendungsbeschreibung:
MCE Product type: Reference compound
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