GSK-872 hydrochloride (Standard), CAS [[2703752-81-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-101872AR
Hersteller Artikelnummer:
HY-101872AR
Alternativnummer:
MCE-HY-101872AR-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
GSK-872 hydrochloride (Standard) is the analytical standard of GSK-872 hydrochloride (HY-101872A). This product is intended for research and analytical applications. GSK-872 hydrochloride is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. GSK-872 hydrochloride decreases the RIPK3-mediated necroptosis and subsequent cytoplasmic translocation and expression of HMGB1, as well as ameliorates brain edema and neurological deficits in early brain injury[1][2][3].
Molekulargewicht:
419.95
CAS Nummer:
[2703752-81-0]
Formel:
C19H18ClN3O2S2
Target-Kategorie:
Reference Standards,RIP kinase
Anwendungsbeschreibung:
MCE Product type: Reference Standards
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