3MB-PP1, a bulky purine analog, is a Polo-like kinase 1 (Plk1) inhibitor. 3MB-PP1 blocks mitotic progression and cell division arise through target Plk1 in in cells expressing analog-sensitive Plk1 alleles. 3MB-PP1 specifically inhibits the activity of analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK, IC50=2 µM). 3MB-PP1 can be used for the research of hypha formation of Candida albicans and cell division[1][2][3].
Molekulargewicht:
295.38
Reinheit:
99.66
CAS Nummer:
[956025-83-5]
Formel:
C17H21N5
Target-Kategorie:
CDK,DAPK,Polo-like Kinase (PLK)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
