Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 µM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit alpha1beta2gamma2 with an ED50 value of 143 µM, a full agonist efficacy at alpha5 subunit (ED50=28-129 µM) and a superagonist efficacy at alpha4beta3delta (ED50=6 µM). Gaboxadol hydrochloride is a non-opioid agent[1][2].
Molekulargewicht:
176.60
Reinheit:
99.95
CAS Nummer:
[85118-33-8]
Formel:
C6H9ClN2O2
Target-Kategorie:
GABA Receptor
Anwendungsbeschreibung:
Reference compound
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