Simeprevir (Standard), CAS [[923604-59-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-10241R
Hersteller Artikelnummer:
HY-10241R
Alternativnummer:
MCE-HY-10241R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Simeprevir (Standard) is the analytical standard of Simeprevir (HY-10241). This product is intended for research and analytical applications. Simeprevir (TMC435, TMC435350) is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a Ki of 0.36 nM. Simeprevir inhibits HCV replication with an EC50 of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (Mpro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses[1][4].
