Adezmapimod, CAS [[152121-47-6]]

Produktübersicht

• Artikelname: Adezmapimod, CAS [[152121-47-6]]
• Artikelnummer: MCE-HY-10256
• Hersteller Artikelnummer: HY-10256
• Alternativnummer: MCE-HY-10256-5MG,MCE-HY-10256-10MG,MCE-HY-10256-50MG,MCE-HY-10256-200MG,MCE-HY-10256-10MMX1ML,MCE-HY-10256-500MG,MCE-HY-10256-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: SB 203580, RWJ 64809

Produktbeschreibung

Adezmapimod (SB 203580) is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38beta2, respectively. Adezmapimod inhibits LCK, GSK3beta and PKBalpha with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod can inhibit p38 MAPK and lead to the inhibition of downstream HSP27 phosphorylation. Adezmapimod does not disrupt JNK activity and is an autophagy and mitophagy activator[1][2][3].

Produkteigenschaften

• Molekulargewicht: 377.43
• Reinheit: 99.96
• CAS Nummer: [152121-47-6]
• Formel: C21H16FN3OS
• Target-Kategorie: Autophagy,HSP,Mitophagy,Organoid,p38 MAPK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound