(-)-Enitociclib, CAS [[1610408-96-2]]

Produktübersicht

• Artikelname: (-)-Enitociclib, CAS [[1610408-96-2]]
• Artikelnummer: MCE-HY-103019B
• Hersteller Artikelnummer: HY-103019B
• Alternativnummer: MCE-HY-103019B-50MG,MCE-HY-103019B-5MG,MCE-HY-103019B-2MG,MCE-HY-103019B-10MG,MCE-HY-103019B-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: (R)-Enitociclib, (-)-BAY-1251152, (-)-VIP152

Produktbeschreibung

(-)-Enitociclib ((R)-Enitociclib) is an enantiomer of Enitociclib (HY-103019E) with an optical rotation of (-). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II, thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC+ lymphoma and multiple myeloma (MM) cells, and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003), and can be used in the research of hematological malignancies[1][2].

Produkteigenschaften

• Molekulargewicht: 404.43
• Reinheit: 99.85
• CAS Nummer: [1610408-96-2]
• Formel: C19H18F2N4O2S
• Target-Kategorie: Apoptosis,CDK,DNA/RNA Synthesis,Drug Isomer

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound