Azepexole hydrochloride (B-HT 933 dihydrochloride, Oxazoloazepin dihydrochloride) is a selective agonist for alpha 2-adrenoceptor, with pKi of 8.3, 7.6, and 7.5 for alpha2A-, alpha2B- and alpha2C-adrenoceptor subtypes, resepctively. Azepexole dihydrochloride causes concentration-dependent inhibition of peristaltic contractions with IC50 of 78.72 nM. Azepexole hydrochloride exhibits antitussive and analgesic efficacy[1][2].
Molekulargewicht:
217.70
Reinheit:
99.89
CAS Nummer:
[147663-20-5]
Formel:
C9H16ClN3O
Target-Kategorie:
Adrenergic Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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