Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Abeta plaques. Methoxy-X04 retains in vitro binding affinity for amyloid b (Ab) fibrils (Ki= 26.8 nM). Methoxy-X04 is fluorescent and stains plaques, tangles, and cerebrovascular amyloid in postmortem sections of AD brain with good specificity[1][2].
Molekulargewicht:
344.40
Reinheit:
98.47
CAS Nummer:
[863918-78-9]
Formel:
C23H20O3
Target-Kategorie:
Amyloid-beta
Anwendungsbeschreibung:
MCE Product type: Dye Reagents
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