Ro 90-7501 (Standard), CAS [[293762-45-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-103241R
Hersteller Artikelnummer:
HY-103241R
Alternativnummer:
MCE-HY-103241R-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Ro 90-7501 (Standard) is the analytical standard of Ro 90-7501 (HY-103241). This product is intended for research and analytical applications. Ro 90-7501 is an amyloid beta42 (Abeta42) fibril assembly inhibitor that reduces Abeta42-induced cytotoxicity (EC50 of 2 µM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. RO 90-7501 selectively enhances toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) ligand-induced IFN-beta gene expression and antiviral response[2]. Ro 90-7501 also inhibits protein phosphatase 5 (PP5) in a TPR-dependent manner[3]. Ro 90-7501 has significant radiosensitizing effects on cervical cancer cells[4].
