Xestospongin C ((-)-Xestospongin C) is a selective, reversible inositol 1,4,5-trisphosphate receptor (IP3R) inhibitor. Xestospongin C acts as an inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) pump of internal stores. Xestospongin C blocks IP3-induced Ca2+ release from cerebellar microsomes with an IC50 of 358 nM. Xestospongin C is a valuable tool for investigating the structure and function of IP3Rs and Ca2+ signaling in neuronal and nonneuronal cells[1][2][3].
Molekulargewicht:
446.71
Reinheit:
99.9
CAS Nummer:
[88903-69-9]
Formel:
C28H50N2O2
Target-Kategorie:
Apoptosis,Calcium Channel
Anwendungsbeschreibung:
MCE Product type: Natural Products
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