(1R,2R)-Calhex 231 hydrochloride is the isomer of Calhex 231 hydrochloride (HY-103320A), and can be used as an experimental control. Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39 µM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment[1][2].
Molekulargewicht:
443.41
Reinheit:
98.45
Formel:
C25H28Cl2N2O
Target-Kategorie:
CaSR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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