C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [35S]GTPgammaS from binding to the receptor with an IC50 of 18 nM[1].
Molekulargewicht:
540.57
Reinheit:
99.92
CAS Nummer:
[1784252-84-1]
Formel:
C27H43Cl2N5O2
Target-Kategorie:
CCR
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
