EGFR/ErbB-2/ErbB-4 inhibitor-3 (compound 29) is a potent tyrosine kinase inhibitor with IC50s of 0.3, 1.1, 0.5, 2.5, 24 nM for erbB1, erbB2, erbB4, EGF, HER, respectively[1]. EGFR/ErbB-2/ErbB-4 inhibitor-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molekulargewicht:
355.75
Reinheit:
98.19
CAS Nummer:
[881001-19-0]
Formel:
C17H11ClFN5O
Target-Kategorie:
EGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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