Ladostigil (TV-3326) hemitartrate is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO) that can cross the blood-brain barrier, with IC50s of 37.1 and 31.8 µM for MAO-B and AChE, respectively. Ladostigil hemitartrate exhibits neuroprotective, antioxidant and anti-inflammatory activities. Ladostigil hemitartrate can be used for the research of depression and Alzheimers disease[1][2]. Ladostigil (hemitartrate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molekulargewicht:
694.77
Reinheit:
98.90
CAS Nummer:
[209394-46-7]
Formel:
C16H20N2O2.1/2C4H6O6
Target-Kategorie:
Cholinesterase (ChE),Monoamine Oxidase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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