BAY-320 is a selective and ATP-competitive Bub1 inhibitor that inhibits the kinase activity of Bub1 with an IC50 of 680 nM. BAY-320 inhibits endogenous Bub1-mediated Sgo1 localization. BAY-320 affects cellular mitotic chromosome arrangement and spindle assembly. BAY-320 inhibits cell proliferation. BAY-320 can be used in the study of cancer such as ovarian cancer and cervical cancer[1][2].
Molekulargewicht:
492.52
Reinheit:
99.74
CAS Nummer:
[1445830-50-1]
Formel:
C26H26F2N6O2
Target-Kategorie:
Ser/Thr Kinase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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