Islatravir (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Islatravir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molekulargewicht:
293.25
Reinheit:
99.67
CAS Nummer:
[865363-93-5]
Formel:
C12H12FN5O3
Target-Kategorie:
HIV,Reverse Transcriptase
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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