MKC8866, CAS [[1338934-59-0]]

Produktübersicht

• Artikelname: MKC8866, CAS [[1338934-59-0]]
• Artikelnummer: MCE-HY-104040
• Hersteller Artikelnummer: HY-104040
• Alternativnummer: MCE-HY-104040-50MG,MCE-HY-104040-25MG,MCE-HY-104040-5MG,MCE-HY-104040-10MMX1ML,MCE-HY-104040-100MG,MCE-HY-104040-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Orin1001

Produktbeschreibung

MKC8866, a salicylaldehyde analog, is a potent, selective IRE1 RNase inhibitor with an IC50 of 0.29 µM in human vitro. MKC8866 strongly inhibits Dithiothreitol-induced X-box-binding protein 1-spliced (XBP1s) expression with an EC50 of 0.52 µM and unstresses RPMI 8226 cells with an IC50 of 0.14 µM[1]. MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibits prostate cancer (PCa) tumor growth[2].

Produkteigenschaften

• Molekulargewicht: 361.35
• Reinheit: 99.95
• CAS Nummer: [1338934-59-0]
• Formel: C18H19NO7
• Target-Kategorie: IRE1

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound