Vorasidenib, CAS [[1644545-52-7]]

Produktübersicht

• Artikelname: Vorasidenib, CAS [[1644545-52-7]]
• Artikelnummer: MCE-HY-104042
• Hersteller Artikelnummer: HY-104042
• Alternativnummer: MCE-HY-104042-50MG,MCE-HY-104042-5MG,MCE-HY-104042-1G,MCE-HY-104042-10MMX1ML,MCE-HY-104042-2MG,MCE-HY-104042-500MG,MCE-HY-104042-100MG,MCE-HY-104042-25MG,MCE-HY-104042-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: AG-881

Produktbeschreibung

Vorasidenib (AG-881) is an orally available, brain penetrant second-generation dual mutant isocitrate dehydrogenases 1 and 2 (mIDH1/2) inhibitor. Vorasidenib (AG-881) exhibits nanomolar inhibition of (D)-2-hydroxyglutarate (D-2-HG), and the IC50 ranges of 0.04~22 nM against IDH1 R132C, IDH1 R132G, IDH1 R132H and IDH1 R132S and 7~14 nM against IDH2 R140Q and 130 nM against IDH2 R172K. Vorasidenib can be used for the study of grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1/2 mutation[1][2].

Produkteigenschaften

• Molekulargewicht: 414.74
• Reinheit: 99.87
• CAS Nummer: [1644545-52-7]
• Formel: C14H13ClF6N6
• Target-Kategorie: Isocitrate Dehydrogenase (IDH)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound