rel-Talmapimod (hydrochloride), CAS [[879132-01-1]] Preis auf Anfrage
Artikelnummer:
MCE-HY-10406B
Hersteller Artikelnummer:
HY-10406B
Alternativnummer:
MCE-HY-10406B-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
rel-SCIO-469 (hydrochloride)
rel-Talmapimod (rel-SCIO-469) hydrochloride is an orally active and selective inhibitor of p38alpha MAPK with an IC50 of 9 nM. rel-Talmapimod hydrochloride inhibits the secretion of inflammatory factors (such as TNFalpha, IL-1beta, IL-6, and VEGF) by suppressing the p38alpha MAPK pathway, and it also inhibits angiogenesis and osteoclast activation. rel-Talmapimod hydrochloride inhibits the growth of multiple myeloma cells and induces apoptosis. rel-Talmapimod hydrochloride can be used to study various hematological malignancies (such as multiple myeloma, myelodysplastic syndrome)[1][2][3][4].
