Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59 nM)[1][2].
Molekulargewicht:
374.82
Reinheit:
99.37
CAS Nummer:
[863406-85-3]
Formel:
C17H19ClN6O2
Target-Kategorie:
Na+/H+ Exchanger (NHE)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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