CEB-1604 is an NMDA receptor antagonist. CEB-1604 inhibits NMDA-induced currents in oocytes transfected with NMDA receptor isoforms (NR1/NR2A, NR1/NR2B, NR1/NR2C, NR1/NR2D) with IC50 values ranging from 5 to 12 µM. CEB-1604 abolishes NMDA-dependent epileptiform discharges in rat cortical wedge preparations and reduces the depolarizing effects of NMDA. CEB-1604 can be used in the research field of neurological damage diseases[1].
Molekulargewicht:
255.40
CAS Nummer:
[287173-08-4]
Formel:
C18H25N
Target-Kategorie:
iGluR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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