IQ 1 is a Wnt/beta-catenin/CBP signalling sustainer. IQ 1 maintains long-term expansion of Wnt/beta-catenin-driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing beta-catenin/CBP-mediated transcription and preventing conversion to beta-catenin/p300-mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion[1].
Molekulargewicht:
362.42
Reinheit:
99.13
CAS Nummer:
[331001-62-8]
Formel:
C21H22N4O2
Target-Kategorie:
Wnt
Anwendungsbeschreibung:
MCE Product type: Reference compound
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