L-652343 is a dual cyclooxygenase/lipoxygenase inhibitor. L-652343 can inhibit the production of LTB4 in isolated human polymorphonuclear leukocytes treated with Calcimycin (HY-N6687) (IC50: 1.4 µM), but it is inactive in whole blood. L-652343 can be used in the research of inflammatory and immune diseases[1].
Molekulargewicht:
445.48
CAS Nummer:
[107008-29-7]
Formel:
C22H14F3NO2S2
Target-Kategorie:
COX,Leukotriene Receptor,Lipoxygenase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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