F-14512 (hydrochloride), CAS [[866874-39-7]] Preis auf Anfrage
Artikelnummer:
MCE-HY-106031A
Hersteller Artikelnummer:
HY-106031A
Alternativnummer:
MCE-HY-106031A-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
F-14512 hydrochloride is an anticancer agent that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 hydrochloride enhances the affinity of polyamines for DNA, thereby inhibiting topoisomerase II and achieving selective cellular uptake. F-14512 hydrochloride exhibits significant cytotoxicity against cells with high PTS activity and induces DNA damage. F-14512 hydrochloride demonstrates potent antitumor activity in the MX1 breast tumor xenograft model. F-14512 hydrochloride could be used to study breast cancer[1].
Molekulargewicht:
787.60
CAS Nummer:
[866874-39-7]
Formel:
C33H51Cl4N5O8
Target-Kategorie:
DNA/RNA Synthesis,Topoisomerase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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