F-14512 (hydrochloride), CAS [[866874-39-7]] Preis auf Anfrage

Artikelnummer: MCE-HY-106031A
Artikelname: F-14512 (hydrochloride), CAS [[866874-39-7]] Preis auf Anfrage
Artikelnummer: MCE-HY-106031A
Hersteller Artikelnummer: HY-106031A
Alternativnummer: MCE-HY-106031A-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
F-14512 hydrochloride is an anticancer agent that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 hydrochloride enhances the affinity of polyamines for DNA, thereby inhibiting topoisomerase II and achieving selective cellular uptake. F-14512 hydrochloride exhibits significant cytotoxicity against cells with high PTS activity and induces DNA damage. F-14512 hydrochloride demonstrates potent antitumor activity in the MX1 breast tumor xenograft model. F-14512 hydrochloride could be used to study breast cancer[1].
Molekulargewicht: 787.60
CAS Nummer: [866874-39-7]
Formel: C33H51Cl4N5O8
Target-Kategorie: DNA/RNA Synthesis,Topoisomerase
Anwendungsbeschreibung: MCE Product type: Reference compound