Rucaparib (AG014699) hydrochloride is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib hydrochloride is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib hydrochloride has the potential for castration-resistant prostate cancer (CRPC) research[1][2][3][4].
Molekulargewicht:
359.83
CAS Nummer:
[773059-19-1]
Formel:
C19H19ClFN3O
Target-Kategorie:
PARP
Anwendungsbeschreibung:
MCE Product type: Reference compound
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