Niraparib (Standard) is the analytical standard of Niraparib. This product is intended for research and analytical applications. Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity[1][2][3].
Molekulargewicht:
320.39
CAS Nummer:
[1038915-60-4]
Formel:
C19H20N4O
Target-Kategorie:
Apoptosis,PARP,Reference Standards
Anwendungsbeschreibung:
Reference Standards
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