BIO-11006 is a peptide that inhibits the function of the MARCKS protein. BIO-11006 attenuates LPS-induced neutrophil influx into the lungs, NF-kappaB activation, and expression of the proinflammatory cytokines KC and TNF-alpha. BIO-11006 also reverses disease progression in an LPS-induced mouse lung injury model. BIO-11006 is indicated for research on acute lung injury/acute respiratory distress syndrome (ALI/ARDS)[1].
Molekulargewicht:
1050.17
CAS Nummer:
[901117-03-1]
Formel:
C46H75N13O15
Target-Kategorie:
MARCKS
Anwendungsbeschreibung:
Peptides
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