Sabcomeline (hydrochloride), CAS [[159912-58-0]]

Produktübersicht

• Artikelname: Sabcomeline (hydrochloride), CAS [[159912-58-0]]
• Artikelnummer: MCE-HY-106432A
• Hersteller Artikelnummer: HY-106432A
• Alternativnummer: MCE-HY-106432A-100MG,MCE-HY-106432A-50MG,MCE-HY-106432A-25MG,MCE-HY-106432A-10MG,MCE-HY-106432A-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: SB-202026 (hydrochloride), Memric (hydrochloride)

Produktbeschreibung

Sabcomeline hydrochloride is a muscarinic receptor agonist capable of crossing the blood-brain barrier. Sabcomeline hydrochloride exhibits affinity for all hM1 to hM5 subtypes (pKi=6.72-7.23), and shows near-full agonism at the hM3 receptor, inducing extracellular acidification. Sabcomeline hydrochloride alters the binding kinetics of dopamine D2 receptors through neural network regulation. Sabcomeline hydrochloride also causes minimal cardiovascular changes, effectively reverses spatial memory deficits in rodents and induces conditioned taste aversion. Sabcomeline hydrochloride is an important tool compound in studies of Alzheimers disease and related neurodegenerative diseases[1][2][3].

Produkteigenschaften

• Molekulargewicht: 229.71
• Reinheit: 99.81
• CAS Nummer: [159912-58-0]
• Formel: C10H16ClN3O
• Target-Kategorie: Dopamine Receptor,mAChR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound