YM114 (KAE-393) is a highly potent and selective (5-HT)3-receptor antagonist that does not affect Veratridine (HY-N6691)- or electrical stimulation-induced bradycardia in anesthetized rats. YM114 inhibits 2-methyl-5-HT (HY-19358)-induced Bezold-Jarisch reflex, which originates from (5-HT)3-receptor located on the endings of vagal afferent nerves in the heart[1].
Molekulargewicht:
303.79
CAS Nummer:
[153608-99-2]
Formel:
C16H18ClN3O
Target-Kategorie:
5-HT Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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