ZD 9379 (sodium), CAS [[170142-29-7]] Preis auf Anfrage

Artikelnummer: MCE-HY-106969A
Artikelname: ZD 9379 (sodium), CAS [[170142-29-7]] Preis auf Anfrage
Artikelnummer: MCE-HY-106969A
Hersteller Artikelnummer: HY-106969A
Alternativnummer: MCE-HY-106969A-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
ZD 9379 sodium is a competitive glycine/NMDA receptor antagonist, with an IC50 value of 75 nM (glutamate site). ZD 9379 sodium selectively antagonizes the glycine binding site (GlyB site) on the NMDA receptor, inhibiting the binding of glycine to the NMDA receptor and alleviating excitotoxicity. ZD 9379 sodium reduces the frequency of cortical spreading depression (SDs), alleviates energy depletion in the ischemic penumbra, and delays the expansion of infarction. ZD 9379 sodium reduces the infarct volume and improves neurological function in mouse models. ZD 9379 sodium can be used in studies of acute ischemic stroke, etc[1][2].
Molekulargewicht: 406.77
CAS Nummer: [170142-29-7]
Formel: C19H14ClN3NaO4
Target-Kategorie: Glycine Receptor (GlyR),iGluR
Anwendungsbeschreibung: MCE Product type: Reference compound