BMS-394136 (compound 1) is a potent inhibitor of Kv 1.5, with an IC50 of 0.05 µM. BMS-394136 is a selective IKur inhibitor. BMS-394136 dose-dependently prolongs atrial effective refractory period (AERP) and action potential duration (APD) without effecting ventricular effective refractory period (VERP). BMS-394136 can be used for acute atrial ischemia research[1].
Molekulargewicht:
471.35
CAS Nummer:
[343246-73-1]
Formel:
C24H21Cl2FN4O
Target-Kategorie:
Potassium Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound
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