JNJ-10229570 is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-alpha-MSH to cells expressing human MC1R and MC5R, with IC50 values of 270 nM and 200 nM, respectively.
Molekulargewicht:
389.47
Reinheit:
98
CAS Nummer:
[524923-88-4]
Formel:
C22H19N3O2S
Target-Kategorie:
Melanocortin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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