PZ-128 (P1pal-7), a cell-penetrating lipopeptide pepducin, is a first-in-class, specific and reversible protease-activated receptor-1 (PAR1) antagonist. PZ-128 targets the cytoplasmic surface of PAR1 and interrupts signaling to internally-located G (PAR1-G) proteins. PZ-128 has antiplatelet, anti-metastatic, anti-angiogenic and anticancer effects[1][2][3][4].
Molekulargewicht:
1086.46
Reinheit:
99.84
CAS Nummer:
[371131-16-7]
Formel:
C55H99N13O9
Target-Kategorie:
Protease Activated Receptor (PAR)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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