SR 142948 (dihydrochloride)

Produktübersicht

• Artikelname: SR 142948 (dihydrochloride)
• Artikelnummer: MCE-HY-107664A
• Hersteller Artikelnummer: HY-107664A
• Alternativnummer: MCE-HY-107664A-25MG,MCE-HY-107664A-5MG,MCE-HY-107664A-1MG,MCE-HY-107664A-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

SR 142948 dihydrochloride is an orally active and selective non-peptide neurotensin receptor (NT) antagonist with IC50s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 dihydrochloride antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 dihydrochloride blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 dihydrochloride shows blood-brain permeability and can be used in study of psychiatric disorders[1][2].

Produkteigenschaften

• Molekulargewicht: 758.77
• Reinheit: 99.07
• Formel: C39H53Cl2N5O6
• Target-Kategorie: Neurotensin Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1